Description
Buy MOTS-c Peptide Online – 10mg Vials for High-Purity Mitochondrial Research
MOTS-c peptide is a mitochondrial-derived peptide consisting of 16 amino acids, encoded within the mitochondrial open reading frame of the 12S rRNA genome. This research peptide has gained significant attention for its role in metabolic regulation, energy production, and mitochondrial signaling. Laboratory studies focus on how MOTS-c influences glucose uptake, insulin sensitivity, and AMPK pathway activation, making it a valuable tool in metabolic, anti-aging, and mitochondrial research.
Each batch of MOTS-c is high-purity, lyophilized, and third-party tested, ensuring reproducibility and reliability for in vitro and preclinical research.
Peptide Specifications
| Specification | Description |
|---|---|
| Sequence | Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg |
| Molecular Formula | C₁₀₁H₁₅₂N₂₈O₂₂S₂ |
| Molecular Weight | 2174.6 g/mol |
| CAS Number | 1627580-64-6 |
| PubChem CID | 255386757 |
| Synonyms | Mitochondrial open reading frame of the 12S rRNA-c, 12S rRF-encoded mitochondrial peptide |
| Purity | ≥98% (HPLC) |
| Solubility | Soluble in sterile water |
| Storage Conditions | Lyophilized ≤-18 °C, reconstituted 2–8 °C (short term) |
| Physical Appearance | White lyophilized powder |
| Shelf Life | 36 months when stored properly |
| Quality Verification | Third-party tested by certified laboratories |
| Manufacturing Standard | USA-made, pharmaceutical-grade, GMP compliant |
| Intended Application | In vitro research applications only |
Mechanism & Research Rationale
MOTS-c peptide functions as a mitochondrial signaling molecule, regulating metabolic pathways under stress conditions. Key research findings include:
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Metabolic Regulation: Enhances glucose uptake in skeletal muscle cells and modulates insulin sensitivity.
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AMPK Activation: Activates AMP-activated protein kinase to balance cellular energy.
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Energy Production: Influences mitochondrial function and ATP generation.
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Longevity & Anti-Aging Research: Investigated for its potential to improve cellular resilience and metabolic homeostasis.
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Fatty Acid Metabolism: Studied for its effects on lipid utilization and storage in preclinical models.
These properties make MOTS-c a critical tool for researchers studying obesity, metabolic syndrome, and age-related metabolic decline.
MOTS-c Peptide Dosage & Laboratory Use
While exact dosing depends on cell type and experimental design, common research ranges include:
| Experimental Model | Concentration Range | Treatment Duration | Observed Endpoint / Notes |
|---|---|---|---|
| Skeletal muscle or fibroblast cultures | 0.1 – 10 μM | 24–72 hours | AMPK activation, glucose uptake, mitochondrial activity |
| Stem cells or iPSC-derived models | 0.5 – 5 μM | 24–48 hours | Energy metabolism, proliferation, mitochondrial biogenesis |
| Metabolic stress assays | 1 – 10 μM | 12–48 hours | ROS mitigation, ATP production, insulin sensitivity |
| Anti-aging in vitro models | 0.1 – 5 μM | 48–96 hours | Senescence markers, longevity-associated gene expression |
Important: MOTS-c peptide is for laboratory research only, not for human or veterinary use. Researchers should follow institutional protocols and sterile handling procedures.
Potential Research Applications
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Metabolic Regulation: Studying insulin sensitivity and glucose uptake mechanisms.
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Mitochondrial Function: Evaluating energy production, mitochondrial biogenesis, and stress response.
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Muscle Health: Exploring effects on muscle endurance, metabolic efficiency, and recovery.
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Anti-Aging & Longevity Research: Investigating cellular resilience, metabolic homeostasis, and age-related decline.
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Fatty Acid Metabolism: Examining lipid utilization and storage under controlled experimental conditions.
Quality Assurance
Each batch of MOTS-c peptide undergoes:
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Independent third-party testing for purity and sterility
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Endotoxin screening
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GMP-compliant, pharmaceutical-grade production
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Verified molecular sequence and HPLC purity
High Purity Peptides guarantees research-grade quality, ensuring reproducibility and reliable results in laboratory studies.
Where to Buy MOTS-c Peptide Online
USA & Florida
Researchers in the USA can conveniently buy MOTS-c peptide online with verified quality from trusted suppliers. High Purity Peptides provides research-grade MOTS-c with fast domestic shipping to laboratories across Florida, California, New York, Texas, and other states. Orders are processed quickly, often with same-day or next-day shipping, ensuring peptides arrive safely under proper cold-chain conditions.
Bulk & Wholesale Options (China)
For institutions and large-scale research programs, bulk MOTS-c peptide is available from China-based peptide manufacturers. When purchasing bulk quantities, researchers should verify:
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GMP- or ISO-certified production
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HPLC/MS documentation confirming purity
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Compliance with import regulations
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Labeling strictly for research use only
Bulk buying can be cost-effective for large studies, but quality verification and regulatory compliance are essential to maintain research standards.
How to Order MOTS-c Peptide
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Select a verified peptide supplier such as High Purity Peptides.
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Confirm purity and Certificate of Analysis (COA) documentation.
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Place a laboratory or institutional order.
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Ensure proper cold-chain shipping for peptide stability.
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Store lyophilized peptide at ≤–18°C; reconstituted peptide should be kept at 2–8°C and used within 28 days.
By following these steps, researchers can safely purchase MOTS-c peptide for high-quality, reproducible laboratory studies.
